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| Autoimmune disease happens when the body’s natural defense system can’t tell the difference between its own cells and foreign cells, causing the body to mistakenly attack normal cells. Several types of autoimmune diseases affect a wide range of body parts. The tests help estimate disease severity, aid in assessing prognosis and are useful to follow disease activity. | |||||||
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| Order code | Test | Purpose | Specimen | Method | |||
| AID 401 | AChR (Acetylcholine Receptor) Binding Antibody | ACHR antibodies are produced by the immune system and allow communication between nerve and muscle fibers. They mistakenly target proteins in the muscles causing Myasthenia Gravis (MG), an autoimmune disorder with multiple symptoms such as muscle fatigue, drooping eyelids, slurred speech, difficulty holding up their head, difficulty breathing, difficulty walking, and weakness in muscles throughout the body. | Blood | AChR ELISA Kit | |||
| AID 402 | Antineutrophil Cytoplasmic Antibody | Antineutrophil Cytoplasmic Antibodies (ANCA) attack healthy white blood cells (neutrophils) in people with certain types of autoimmune disorders. Most common disorders associated with ANCA are Systemic Valculitis (swelling and inflammation of the blood vessels), and Ulcerative Colitis (a form of inflammatory bowel disease - IBD). The ANCA blood test looks for the two primary types of ANCAs, pANCA and cANCA, which are differentiated according to which type of proteins they attack. ANCA symptoms include red itchy eyes, blurred vision, hearing loss, runny nose, skin rash, cough, difficulty breathing, abdominal cramping, diarrhea, blood in the stool, fever, fatigue, and muscle or joint aches. | Blood | ANCA Complete ELISA Kit | |||
| AID 403 | Actin Smooth Muscle Antibody | Actin Smooth Muscle Antibodies (ASMA) are produced in people with certain types of autoimmune disorders which cause the body's immune system to produce antibodies that attack its own cells and tissues. Smooth muscle antibodies target actin, a type of protein found in various parts of the body. ASMA are typically associated with autoimmune hepatitis which causes inflammation to the liver and can lead to cirrhosis or liver failure with symptoms such as jaundice or fatigue. | Blood | Human Actin Smooth Muscle ELISA Kit | |||
| AID 404 | Adrenal Antibodies | Antiadrenal antibodies or adrenal antibodies are autoimmune antibodies produced when the body's immune system mistakenly targets its own adrenal cortex which is part of the adrenal glands. Damage to the adrenal glands causes a deficiency in several hormones such as cortisol and aldosterone with symptoms of fatigue, weight loss, darkened skin coloration, low blood pressure, low blood sugar, muscle or joint pain, nausea, diarrhea, vomiting, irritability, and depression | Blood | Human Anti-Adrenal cortex antibody ELISA Kit | |||
| AID 405 | Anti-CCP antibodies (Cyclic Citrullinated Peptide) | Anti-CCP antibodies are produced by the body in reaction to an autoimmune disorder, typically Rheumatoid Arthritis with symptoms such as painful swollen joints in the hands or wrists, stiffness in the joints and pain in the elbows, knees, neck, shoulders, hips or feet. | Blood | Anti CCP ELISA Kit - ELISA Kit | |||
| AID 406 | Anti-IgE IgG | IgG antibodies to immunoglobulin E (IgE) are typically associated with hives (Urticaria), red itchy welts that appear on various parts of the skin. Hives can be triggered by a number of disorders including an allergic response. Chronic Urticaria can persist for several weeks. Autoantibodies produced by the immune system mistakenly target mast cells that are responsible for histamine production. This causes the body to react as though it has encountered an allergen which causes the development of hives. Causes of hives can be multiple and unknown. Anti-IgE IgG testing can help determine if the causes of the hives are related to autoimmune disorder. Negative results may rule out an autoimmune disorder as the cause. | Blood | Anti-IgE Antibody ELISA Kit | |||
| AID 407 | Anti-dsDNA | The Anti-dsDNA test is used to aid in the diagnosis of Systemic Lupus Erythematosus and distinguish it from other autoimmune disorders. This test can also be used to monitor Lupus in people who have already been diagnosed with the disease. Symptoms of Lupus may include but are not limited to: Muscle or joint pain, Red rash on the nose and cheek area, Fever, Chronic fatigue, Hair and weight loss, Sensitivity to ultraviolet light | Blood | Anti-dsDNA ELISA | |||
| AID 408 | Anti Extractable Nuclear Antigens (ENA) | Autoantibodies are produced by the body's immune system and mistakenly attack its own cells and tissues. The Extractable Nuclear Antigen (ENA) test looks for the presence of 2 types of autoantibodies (Smith (Sm) Antibodies and Anti-Ribonucleoprotein (RNP). ENA testing is usually done for symptoms that include fever, chronic fatigue, muscle pain, joint swelling, rash, hair loss, sensitivity to sunlight, anemia with low RBC or WBC counts, depression, and seizures. The type of autoantibodies that are present can help make a diagnosis and differentiate between different autoimmune disorders. | Blood | ENA screen ELISA Kit | |||
| AID 409 | Anticardiolipin Antibody IgA, IgG, IgM | Cardiolipins are Phospholipid that plays an important role in blood clotting. In some people with autoimmune disorders such as Lupus, the body produces antibodies to target its own Cardiolipins causing abnormal blood clotting. Blood testing for Cardiolipin Antibodies can help determine the cause of conditions associated abnormal blood clotting and aid in the diagnosis of Antiphospholipid Syndrome (APS). | Blood | Human Anti-Cardiolipin IgG/IgM ELISA Kit | |||
| AID 410 | Antinuclear Antibody (ANA) | Antinuclear Antibodies (ANA) attack the nucleus of the body's own cells causing autoimmune disorder such as Lupus, Rheumatoid Arthritis, Sjogren's Syndrome or Scleroderma. Because the symptoms of autoimmune disorders are often similar, ANA testing can narrow down the possible diagnoses. | Blood | ANA Screen ELISA Kit | |||
| AID 411 | Antiparietal Cell Antibody | Parietal cells are in the stomach and produce acid used in digestion, and a protein (intrinsic factor) which helps the body absorb Vitamin B12. People with the autoimmune disorder Pernicious Anemia, produce antibodies that attack parietal cells, causing the inhibition in producing Intrinsic Factor, which in turn prevents the body from properly absorbing vitamin B12. B12 deficiency prevents the normal production of red blood cells which can lead to several health complications. | Blood | Human Parietal Cell ELISA Kit | |||
| AID 412 | C1 Esterase Inhibitor (INH) | C1 is a protein which helps the body protect itself from infections. C1 esterase inhibitor helps control the function of C1. Deficiency in C1-INH can indicate Angioedema with symptoms such as tissue swelling throughout the body (feet, face, hands, throat, and intestines),abdominal pain, vomiting, dehydration, cramping, and a red rash, malnutrition, blood infection, bacterial infection, lupus, and kidney disease. | Blood | Human C1 inhibitor ELISA Kit | |||
| AID 413 | Calprotectin Stool | Calprotectin is a protein released by the white blood cell neutrophils in response to inflammation in the GI tract. Inflammation in the intestines may be caused by inflammatory bowel disease (IBD), Crohn's Disease, ulcerative colitis, or bacterial infections. Symptoms of inflammatory GI disorders include abdominal pain, diarrhea, fever, weight loss, and rectal bleeding. While a calprotectin test cannot identify a specific condition, it can help distinguish between inflammatory and non-inflammatory conditions affecting the intestines. | Fecal | Quantitative Calprotectin ELISA Kit | |||
| AID 414 | Centromere B Antibody Test | Centromere B antibodies are found in people with CREST syndrome, a connective tissue disease. CREST stands for Calcinosis (Calcium deposits forming under the skin), Raynaud phenomenon (Decreased circulation in the fingers and toes), Esophageal dysfunction (Difficulty swallowing, acid reflux, and heart burn), Sclerodactyly (Tight, thick, shiny skin developing on the hands and fingers), Telangiectasia (Red spots that appear on the skin due to swollen capillaries). | Blood | Human Centromere B ELISA Kit | |||
| AID 415 | Cold Agglutinin Titer Blood Test | Cold Agglutinins (CA) are autoantibody which mistakenly target and destroy red blood cells, causing them to clump together. CA are activated when the body is exposed to cold temperatures. They can cause the destruction of RBC's resulting in Hemolytic Anemia. CA Symptoms include fatigue, weakness, pale skin, dizziness, headache. and blue coloring in the extremities. | Blood | Cold agglutinin (CAT) ELISA Kit | |||
| AID 416 | Complement Total Ch50 Blood Test | The Complement system is a series of 30-60 proteins that work to promote the function of the immune system and its response to inflammation and infection. When one or more components of the complement system are deficient, it can lead to an inability to properly fight off infections or the development of an autoimmune disorder. Abnormal results for a Total Complement test are often followed up with a test that measures a specific type of protein. | Blood | Ch50 ELISA Kit | |||
| AID 417 | Celiac Genetic Blood | The 2 genes HLA-DQ2 and HLA-DQ8 are mainly associated with Celiac. While not every person who has these genes will develop Celiac, most people with Celiac have one or both of these genes present. Genetic testing for Celiac is typically ordered as either a confirmation for positive results from other Celiac blood tests or to aid in diagnosis when a person's test results are inconclusive. | Blood | Celiac Disease Test Kit, | |||
| AID 418 | Endomysial Antibody, IgA Blood | Endomysial Antibody IgA testing is used in the diagnosis of Celiac Disease. However, not all people with Celiac disease will develop Endomysial antibodies. For this reason, additional testing may be necessary. | Blood | Human EMA IgA ELISA Kit | |||
| AID 419 | Gliadin Antibody IgA/IgG Test | Celiac is an autoimmune disorder in which the body's immune system attacks the lining of the small intestine following person consumption. Antibodies to Gliadin, a component of wheat, are often found in people with Celiac. | Blood | Human Anti-Gliadin IgA Antibody ELISA Kit | |||
| AID 420 | Glutamic Acid Decarboxylase GAD65 Antibody | Glutamic Acid Decarboxylase is an enzyme which plays a role in nervous system function. Certain autoimmune disorders can cause the production of GAD autoantibodies which attack cells in the pancreas, responsible for the production of insulin. The inability to properly produce insulin can lead to the development of diabetes. A GAD antibody are mostly elevated with Type 1 Diabetes | Blood | Glutamic acid ELISA Kit | |||
| AID 421 | HLA B27 Blood | The HLA B27 test looks for a specific protein, also known as a Human Leukocyte Antigen, that is commonly associated with Ankylosing Spondylitis and other forms of Arthritis. Ankylosing Spondylitis is a form of arthritis which affects the vertebrae in the spine. Approximately 88% of people with Ankylosing Spokdylitis test positive for HLA B27. IgA antibodies are typically found in areas of the body such as the digestive tract, ears, eyes, breathing | Blood | HLA-B27 ELISA Kit | |||
| AID 422 | Immunoglobulin A IgA | passages, saliva, tears and blood. Some people however have a condition which causes their body to not produce IgA antibodies. Elevated IgA levels can be indicative of a number of conditions such as Rheumatoid Arthritis, Lupus, Cirrhosis and Hepatitis. This condition may not cause immediate health concerns but has the potential of developing into Multiple Myeloma. People with low IgA levels have a higher risk of developing of autoimmune disorders, Leukemia, kidney disease and intestinal disease. | Blood | Human Immunoglobulin A, IgA ELISA Kit | |||
| AID 423 | IgG Blood | passages, saliva, tears and blood. Some people however have a condition which causes their body to not produce IgA antibodies. Elevated IgA levels can be indicative of a number of conditions such as Rheumatoid Arthritis, Lupus, Cirrhosis and Hepatitis. This condition may not cause immediate health concerns but has the potential of developing into Multiple Myeloma. People with low IgA levels have a higher risk of developing of autoimmune disorders, Leukemia, kidney disease and intestinal disease. | Blood | Human Immunoglobulin A, IgA ELISA Kit | |||
| AID 424 | IgM Blood | Immunoglobulin M (IgM) antibody test determine if an infection is present and whether the infection is acute or chronic. | Blood | IgG ELISA Kit | |||
| AID 425 | Indican (Obermeyer) Urine | Indican is a byproduct of bacteria in the intestines breaking down protein. Normally, there is little to no indican in urine. Elevated urinary indican may result from a highe, than normal amount of protein in the diet, lack of properly digesting protein or an overgrowth of bacteria n their digestive system. Indican urine test can diagnose dysbiosis, an imbalance in the bacterial colonies in the GI tract, Celiac Disease, Crohn's Disease, Ulcerative Colitis, and Irritable Bowel Syndrome, intestinal obstruction, stomach cancer, gastric ulcers, liver disease, and candida infections. Common symptoms for elevated indican include diarrhea, bloating, gas, and stomach pain. | Urine | Indican Obermeyer Test Kit | |||
| AID 426 | Insulin Autoantibodies Blood | Type 1 Diabetes is caused by the body's immune system attacking beta cells in the pancreas which produce insulin. With its insulin production impaired, the body cannot properly manage glucose (blood sugar.). Symptoms include frequent thirst, frequent urination, unexplained weight loss, and wounds that are slow to heal. Insulin autoantibodies test can help determine person at risk for developing type 1 diabetes, diagnose type 1 diabetes and differentiate it from type 2 diabetes which causes similar symptoms. | Blood | Insulin Autoantibodies ELISA Kit | |||
| AID 427 | Interleukin 6 (IL6) Blood Test | Interleukin 6 (IL6) is a protein that plays a role in the body's immune response. Normally IL6 levels are low or undetectable. Elevated levels of IL6 are due to autoimmune disorders, inflammation, infection, some types of cancer, or heart disease. However, IL6 test cannot identify the source of the inflammation. Additional testing will typically be necessary before a diagnosis can be made. | Blood | IL-6 Human ELISA Kit | |||
| AID 428 | Intrinsic Factor Antibody Blood Test | Intrinsic Factor is a protein which binds with Vitamin B12 and allows it to be absorbed by the body. People with Pernicious Anemia (an autoimmune disorder) the immune system produces antibodies against intrinsic factor. This interferes with the normal absorption of vitamin B12. Without sufficient levels of B12, the body cannot produce red blood cells which leads to the development of anemia | Blood | AMH ELISA | |||
| AID 429 | Jo 1 Antibody Blood | Jo-1 is an autoantibody associated with disorders that cause inflammation such as polymyositis which causes muscle weakness in the hips, arms, shoulders, or neck. Polymyositis is often linked to rheumatoid arthritis, cardiovascular disease, lung disease, Sjogren's syndrome, or lupus. | Blood | Jo-1 ELISA Kit | |||
| AID 430 | Liver Kidney Microsome (LKM) Antibody Test | Liver-Kidney Microsome (LKM) antibodies autoantibodies that primarily targets the liver. They are typically associated with Type 2 Autoimmune Hepatitis. Hepatitis is a series of conditions that cause inflammation of the liver and can lead to cirrhosis and liver failure. Autoimmune Hepatitis is a disorder in which the body's own immune system mistakenly targets cells in the liver. | Blood | LKM ELISA Kit | Human Liver/Kidney | |||
| AID 431 | Mitochondrial Antibody Blood | Antimitochondrial Antibodies (AMA) are autoantibody which are primarily associated with Primary Biliary Cirrhosis (PBC), an autoimmune disorder that causes inflammation of the bile ducts in the liver. AMA test can diagnose PBC and differentiate it from other conditions that cause liver damage. | Blood | Human Anti-mitochondrial antibody (AMA) ELISA Kit | |||
| AID 432 | Myeloperoxidase (MPO) Antibody Blood | An MPO antibody test is often used to diagnosis of Vasculitis, an autoimmune disorder which causes inflammation of the blood vessels. MPO antibodies are also present in autoimmune disorders including Lupus. When used in conjunction with other tests, MPO Antibodies help differentiate different types of autoimmune diseases. . . | Blood | Myeloperoxidase ELISA Kit | |||
| AID 433 | RNP Antibody Blood | Anti-Ribonucleoprotein or RNP antibodies autoantibody. Elevated RNP antibodies are typically associated with connective tissue disorders such as rheumatoid arthritis, scleroderma, and lupus. Common symptoms of these disorders include muscle and joint pain, swelling and inflammation in the fingers or hands, numbness in the extremities, fatigue, and fever. | Blood | RNP ELISA Kit | Human Anti Ribonucleoprotein Antibody ELISA | |||
| AID 434 | Rheumatoid Arthritis (RA) Factor Blood | Rheumatoid Arthritis (RA) Factor test helps diagnose Rheumatoid Arthritis, an autoimmune disorder which cause pain, stiffness and deterioration in the joints. About 80% of people with Rheumatoid Arthritis will show elevated levels of RA Factor. However, RA Factor may also be found with other conditions such as Sjogren Syndrome, certain types of cancer, various infections and other autoimmune disorders. RA Factor may be present in a small percentage of healthy people as well. | Blood | Rheumatoid Factor Test, RF ELISA Kit | |||
| AID 435 | Scleroderma (Scl-70) Blood Test | The presence of Anti-Scl 70 antibodies is typically associated with the autoimmune disorder Scleroderma, a connective tissue disease that affects the skin and other tissues including blood vessels, organs, and the digestive tract. Common symptoms include developing patches of hardened tightened skin, fingers or toes that turn blue and numb in cold temperatures, heartburn, bloating, cramping, constipation, and diarrhea. | Blood | Human Scl-70 ELISA Kit | |||
| AID 436 | Sedimentation Rate (ESR) Blood Test | The Erythrocyte Sedimentation Rate (ESR) or Sed Rate test is used to measure inflammation in the body. The test measures the rate at which red blood cells settle in a sample. If the cells settle faster, it indicates a higher level of specific proteins which are present in the blood when there is inflammation in the body. The Sed Rate test can help determine if inflammation is present but not the cause of it. . | Blood | Erythrocyte Sedimentation Rate Test | |||
| AID 437 | Sjogren Antibodies Test | This test looks for two types of auto antibodies, SS-A and SS-B, which are commonly associated with Sjogren's Syndrome, an autoimmune disease. Sjogren's typically targets the glands which produce tears and saliva causing symptoms such as dry eyes and mouth. Sjogren's syndrome can also effect the joints, muscles, liver, kidneys, thyroid, lungs and nervous system. | Blood | Sjogren syndrome antigen B ELISA Kit | |||
| AID 438 | TSI Blood Test | The TSI (Thyroid Stimulating Immunoglobulin) Blood Test is used to diagnose autoimmune disorders which affect the Thyroid. In patients suspected have Grave's Disease in which the body produces antibodies which attack the thyroid gland. | Blood | TSI ELISA Kit | |||
| AID 439 | Thyrotropin-Binding Inhibitory Immunoglobulin TBII Blood Test | The Thyroid Binding Inhibitory Immunoglobulin (TBII) is used to diagnose thyroid autoimmune disorders such as Grave's Disease. TBII prevents Thyroid Stimulating Hormone (TSH) from binding to proteins in the thyroid gland. This blocks the production of thyroid hormones which can cause hypothyroidism. | Blood | Thyrotropin-Binding Inhibitory Immunoglobulin TBII Blood Test ELISA Kit | |||
| AID 440 | Thyrotropin Receptor Antibody Test | The Thyrotropin Receptor Antibody (TRAb) Test is used in the diagnosis of autoimmune disorders which affect the Thyroid. TRAb are the cause of Hyperthyroidism in people Grave's Disease. These antibodies stimulate the thyroid gland to overproduce thyroid hormones | Blood | TRAb ELISA Kit | |||
| AID 441 | Tumor Necrosis Factor (TNF Alpha) Blood test | Tumor Necrosis Factor (TNF) is a protein typically produced by white blood cells as part of the body's response to infection. TNF causes inflammation which is part of the normal process through which the body heals. Some autoimmune disorders such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, and psoriasis are associated with increased production of TNF. High levels of TNF are also sometimes seen in people with insulin resistance which can lead to type 2 diabetes. | Blood | TNF-Alpha ELISA Assay Kit | |||